Originally Posted by Trey
Piccolo would win. He'd make copies of himself and Special Beam Cannon 4 Tails Naruto into oblivion.
I doubt he was so powerful in just dragonball, at least not powerful enough to repeatedly launch special beam cannons. Add that to the fact that four-tailed-naruto is very, very fast, he could probably at least move a few inches and dodge a killing blow from the attack.