Originally Posted by MikeyM1979
My memory may be a little off, but Shizune couldn't do anything against someone like Kabuto, right? Hmm. I doubt Sakura could do much against him either. But she is a Tsunade junior. We don't really know what Shizune is capable of.
'' Kabuto? Pre-timeskip kabuto was the one who almost beat Tsunade through sheer intelligence. Don't underestimate him. Shizune > Sakura pretimeskip.