Neji would lose
Anyway Kisame vs Orochimaru huh...
The fact the area is full of sand wouldn't matter because Kisame could just make water to use, but I don't think he could stop Orochimaru with water jutsu and strength.
For example I think Orochimaru is more of a earth(he uses earth replacement jutsu)type like the 3rd and Jiraiya, and we seen how useful brute strenght is against Orochimaru when he fought Tsuande. :O
Kisame would put up a fight but Orochimaru wins this one