The only kid with high possibility of Tsunade's kid is Kabuto. White hair like Dan, high medic like tsunade and like tsunade I dont know what he's thinking.
Not every village do what cloud do. We dont know how the mizukage or other jinchuuriki are related to their kage.
If this theory is true then what is the mizukage relation with madara? His secret son?
Again, Motoi said it was common among the FIVE KAGES. That means the main hidden villages.
If Kishi somehow made a way for Minato be Tsunades son then...
ACT I haven't seen a female Sharingan user either.