I am predicting that Sasuke will become final villain there will be an epic battle between them Sasuke will turn good at last but he feels that he cannot return to Konoha because of the evil things he has done. Also either Sakura will join Sasuke when he leave. or she stays with Naruto and become his wife or something like that..
Also Naruto's ultimate mode will become a fusion between Sage mode and Fox mode
Sasuke will gain a last hax too probably or gain a newer technique when he kills madara or something and fuse the 2 ms