Actually, since I saw the Kanji behind the "Hundred Beasts" title, it really means "of all beasts". Typhon is known as "Father of all monsters", so I can see a resemblance there.
Furthermore, it'd fit the human face Oda already provided for him when talking about the Yonkou and two of the most common words for "monster" in Japanese, kaijuu and kaibutsu, start as you can guess with the Kanji "Kai" (怪, "mystery"). So yeah, there's definitely a possibility there.
PS: that rendition of Typhon is incredibly inaccurate to the traditional Typhon imagery: