Amuro

Nah I'm sorry but unless sasuke has a new Jutsu frm the ems, he cnt deal with tobirama at all. Just because of the time period they grew up in and how many uchihas he's fought in his day. He'd b like Madara kinda....every Jutsu that sasuke pulls out he'll look at it and know exactly what it is how to counter it and its weaknesses ect. Plus he's a Edo and I never saw sasuke seal anyone or anything... Now pro and sasuke would prolly take him out if they jumped him but sasuke vs the 2nd rite now...nah sasuke cnt do it...