Originally Posted by Vengeance
Minato is a melee assassin type who's defensive ability lies soully in his speed. Minato from what we know simply can't tank hits. Minato relys on quick decisive striking to take down opponents however he lacks high level burst damage which is required to effectively take down tanks with high regan capability.
Hashirama is a long range burst damage AOE Mage while simultaneously also being a "Bruiser Tank" capable of one shooting people with a single punch. Coupled with his vastly superior combat experience, natural auto regan, and potentially limitless chakra supply because of Natural Energy Hashirama is the culmination of various combat styles all rolled up into one super dude.
If this were a video game Minato would be a max level Rogue/Assassin using moderately powerful gear bought off the shop keeper while Hashirama is a max level Combat Mage with end game gear found in the most difficult dungeons that has been +10 for maximum effectiveness. Simply put in a pvp situation the Rogue/Assassin(Minato) couldn't hope to best this opponent. His best and only real option would be to simply use his speed to run away from the fight altogether. Hashirama's massive burst damage AOE is simply the ideal counter against an opponent who likes to play keep away using superior speed. Hashirama's burst covers such a large area of the terrain it basically removes places Minato can even run to making his speed simply ineffective and/or useless in this situation.
Playing it by the numbers there's simply no way for Minato to defeat Hashirama.
Though everything you stated is common sense, it has been offered to KYF, so here comes your set of panels over and over again.... He knows exactly his healing abilities, knows that he can hurt internally and die, but he still doesn't have an excuse for the scraped look on his own panel when he's talking about the Kyuubi. You've just fallen into the KYF Blackhole of redundancy.